Approximating the semantic space: word embedding techniques in psychiatric speech analysis
Large language models provide high-dimensional representations (embeddings) of word meaning, which allow quantifying changes in the geometry of the semantic space in mental disorders. A pattern of a more condensed (‘shrinking’) semantic space marked by an increase in mean semantic similarity between words has been recently documented in psychosis across several languages. We aimed to […]
A single composite index of semantic behavior tracks symptoms of psychosis over time
Semantic variables automatically extracted from spontaneous speech characterize anomalous semantic associations generated by groups with schizophrenia spectrum disorders (SSD). However, with the use of different language models and numerous aspects of semantic associations that could be tracked, the semantic space has become very high-dimensional, challenging both theoretical understanding and practical applications. This study aimed to […]
How the TRUSTING App Assesses Relapse Risk Through Speech
Can language reveal early signs of relapse in psychosis and how can AI help assess risk in a safe and trustworthy way? Roya Hüppi, MSc, PhD student at the Psychiatric University Clinic Zurich and the University of Zurich, explains the scientific thinking behind TRUSTING’s speech-based approach. Roya discusses: This video highlights how TRUSTING combines clinical […]
Inside the TRUSTING Study: How Speech-Based AI Could Transform Psychosis Care
How can everyday speech help predict relapse in psychosis, and what does it take to run a large, international clinical study to make this possible? In this video, Lucia Bautista, PhD, Clinical Trial Manager at the Psychiatric University Clinic Zurich and the University of Zurich, explains the clinical study behind the TRUSTING project. Lucia walks […]
TRUSTING at Europe’s Leading Brain Health Events
In October 2025, Amsterdam & Brussels, TRUSTING took part in two of Europe’s leading events on brain and mental health innovation this month: the ECNP Congress 2025 in Amsterdam and Brain Innovation Days 2025 in Brussels. Showcasing Mental Health Innovation in Europe Both events brought together scientists, clinicians, innovators, policymakers, and patient representatives who share […]
AI detects early signs of psychosis through everyday speech
Researchers at the University Medical Center Groningen (UMCG) use artificial intelligence (AI) to spot subtle changes in everyday speech that may reveal early signs of psychosis. Their research, featured by science journalist Maya Schutte on NEMO Kennislink, shows how language and AI can work together to improve mental health care, including research linked to the […]
TRUSTING Newsletter Volume II: A Turning Point in 2025
The second edition of the TRUSTING newsletter is now online! This issue captures a pivotal moment in TRUSTING’s journey, completing the second year and preparing to move into real-world testing of our speech-based psychosis relapse detection tool. In the foreword, Work Package 2 leader Professor Wolfram Hinzen reflects on the solid foundations built so far: This […]
TRUSTING Newsletter Volume 2
Explore new findings showing that voice alone can signal early signs of psychosis, and find out how TRUSTING is preparing to bring its AI tool into real-world clinical trials across five countries.
Language Use and Self-Perception: A Window to Mental Health
The TRUSTING research aims to improve the early detection of psychotic relapse through speech-based monitoring. A recent article adds valuable insight to this objective: a meta-analysis spanning 80 years of research and 13 studies has found that people with schizophrenia use first-person pronouns, such as “me”, “myself”, and “I”, significantly more often than those without […]
TRUSTING Annual Meeting 2025 in Barcelona Advancing speech-based relapse prediction in psychosis care
TRUSTING project—a five-year European research initiative (2023–2028) working to develop a user-friendly, trustworthy speech-based clinical decision support system to predict relapse in individuals with psychosis – has held its 2025 Annual Meeting from 17–18 June at Universitat Pompeu Fabra (UPF) in Barcelona, convening project partners from across Europe. Hosted by UPF, as project partner, the […]
